Knowledgebase of human thermoregulation ("Termo_Reg_Human 1.0")

Figure 1. Scheme of the database ThermoReg_Human

The table Genes_all

Field	Description
ID_Gene	Unique identifier of the gene in the database EntrezGene
Symbol	The symbol of the gene from the database EntrezGene
Name	The full name of the gene from the database EntrezGene
ID_KEGG	Unique identifier of the gene from the database KEGG GENES

The table Genes_evol

Field	Description
ID_Gene	Unique identifier of the gene in the database EntrezGene
Type	Type of product encoded by the gene (protein or microRNA)
Interactions	Number of Interactions in the network for this gene
GeneOntology	Is the gene associated with thermoregulation according to Gene Ontology data? Answer options: yes/no
ANDSystem	Is the gene associated with thermoregulation according to ANDSystem data? Answer options: yes/no
EntrezGene	Is the gene associated with thermoregulation according to EntrezGene data? Answer options: yes/no
PAI	Phylostratigraphic age of the gene
DI	Gene's evolutionary variability index

The table Proteins

Field	Description
ID_UniProtKB	Unique identifier of the protein in the database UniProtKB
FullName	The full name of the protein
NetName	The name of the protein in the network
GeneID	Unique identifier of the ptotein-coding gene in the database EntrezGene
Interactions	Number of Interactions in the network for this protein
RegInter_microRNA	Number of regulatory interactions with microRNAs from the network, regulating the expression of this protein
microRNAs	List of microRNAs that regulate this protein

The table microRNA

Field	Description
GeneID	Unique identifier of the microRNA-coding gene in the database EntrezGene
NetName	The name of the microRNA in the network
Interactions	Number of Interactions in the network for this microRNA
NumProtein	The number of proteins whose expression is regulated with the participation of this microRNA
Proteins	Names of proteins regulated by this microRNA